Lxxi. Studies in the Biochemistry of Micro-organisms Lxi. the Molecular Constitution of Geodin and Erdin, Two Chlorine-containing Meta- Bolic Products of Aspergillus Terreus Thom. Part Ii. Dihydrogeodin and Dihydroerdin and the Synthesis of Their Trimethyl Ethers
نویسنده
چکیده
RAISTRICK & SMITH [1936] showed that a strain of Aspergillu8 terreus Thomr, when grown on Czapek-Dox solution containing glucose as sole source of carbon and KCI as sole source of chlorine, produced two new metabolic products, geodin,. C15H605C12(0CH3)2, and erdin, C15H706C12(OCH3), each of which on catalytic reduction gave rise to a dihydro-derivative. Later, Clutterbuck et al. [1937] found that both dihydrogeodin and dihydroerdin yielded the same compound on complete methylation with diazomethane, viz. a neutral substance
منابع مشابه
Heterologous Reconstitution of the Intact Geodin Gene Cluster in Aspergillus nidulans through a Simple and Versatile PCR Based Approach
Fungal natural products are a rich resource for bioactive molecules. To fully exploit this potential it is necessary to link genes to metabolites. Genetic information for numerous putative biosynthetic pathways has become available in recent years through genome sequencing. However, the lack of solid methodology for genetic manipulation of most species severely hampers pathway characterization....
متن کاملKINETIC STUDIES USING SEMI-EMPIRICAL SELF- CONSISTENT FIELD (SCF) MOLECULAR ORBITAL (MO) METHOD: PART I1 [I] A MODIFIED NEGLECT OFDIATOMIC OVERLAP (MNDO) STUDY OF THE PYROLYSES OF CHLOROETHYL VINYL ETHERS
The effect of monochloro and dichloro substitution into the ethyl portion on the pyrolysis of ethyl vinyl ether has been studied. This involved four possible monosubstituted derivatives and six disubstituted derivatives. For the monochloro derivatives, B- chloro substitution enhanced the rate constant while a- chloro substitution depressed it noticeably. For the dichloro derivatives, substi...
متن کاملIsolation and characterization of a fungus for extracellular synthesis of small selenium nanoparticles
The use of biogenic selenium nanoparticles for various purposes is going to be an issue of considerable importance; thus, appropriate simple methods should be developed and tested for the synthesis and recovery of these nanoparticles. In this study, a fungus was isolated from a soil sample, identified as Aspergillus terreus and used for extracellular synthesis of selenium nanoparticles (Se NPs)...
متن کاملOne-dimensional Uranium(VI) Coordination Polymer Complex Containing Dimethyl and Trimethyl Phosphate Ligands: Synthesis, Spectroscopic Characterization, Thermal Analyses, and Crystal Structure
A new one-dimensional uranium(VI) coordination polymer, [UO2(μ-DMP)2(TMP)]n (1) (DMP is dimethyl phosphate and TMP is trimethyl phosphate), was prepared from the reaction of UO2(NO3)2.6H2O and TMP in in THF (THF is tetrahydrofuran) as a solvent. Suitable crystals of this complex for crystal structure determination were obtained by slow evaporation of the produced yellow solution at room tempera...
متن کاملLxxi. Studies in the Biochemistry of Micro-organisms
THE name Aspergillus terreus is used by Thom and Church [1918; 1926] to cover a series of strains which have a number of well-marked morphological features in common, but which show a certain amount of variation in colour and type of growth. The conidial colour may range from pale cinnamon to fairly deep brown; the texture of the surface growth may vary from smooth velvety to definitely floccos...
متن کامل